Santalol is an organic compound that is responsible for creating the soothing, sweet, woody aroma in sandalwood. It also comprises 70-90% of the essential oil of sandalwood, which has been found to have a wide range of health benefits.
A 2017 systematic review was published of 12 randomized clinical trials which had studied the effectiveness of aromatherapy using sandalwood and other oils in alleviating depressive symptoms. During these trials, aromatherapy showed potential to be used as an effective therapeutic option for the relief of depressive symptoms in a wide variety of subjects. 1
Results of a 2017 study suggest that inhalation aromatherapy containing santalol may improve difficulties in maintaining sleep in elderly people with dementia. 1